ConPlex
ConPlex is a web application for evolutionary analysis of protein complex structures. With given protein complex structures, ConPlex automatically identifies protein interfaces and carries out evolutionary conservation analyses for the identified regions.

Submission Pre-calculated Library Article Abstracts Backgrounds Instructions Output Example

Job Submission

Input Options
   
  0%
Chain.1
Chain.2
Name
E-mail (Optional)

   

[Input Example] [Download Sample Decoy]

Advanced Options

No. of PSI-BLAST Iteration
PSI-BLAST E-Value Cutoff
Number of homologues MIN:  /  MAX: 
Sequence Identity Cutoff MIN:  /  MAX: 
Core/Rim SASA Cutoff


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Programmatic Interface

For batch-scripting of ConPlex, we provide programmatic interface based on Web Service Description Language (WSDL)

Citations

For publication of results, please cite:

  • ConPlex webservice:

    ConPlex: a web server for evolutionary conservation analysis of protein complex structures.
    Choi YS, Han SK, Kim J, Yang JS, Jeon J, Ryu SH, Kim S.
    Nucleic Acids Research. 2010 Apr 30. [Epub ahead of print].

    View the abstract (PubMed).       Download the full article in PDF.

  • Original research paper:

    Evolutionary conservation in multiple faces of protein interaction.
    Choi YS, Yang JS, Choi Y, Ryu SH, Kim S.
    Proteins. 2009 Feb 27;77(1):14-25. [Epub ahead of print].

    View the abstract (PubMed).       Download the full article in PDF.

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