PDZ domain Specificity Prediction

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This web service predicts the binding specificity of a query PDZ domain. The program automatically extracts the pocket residues of a PDZ domain from a query sequence and generates a position weight matrix (PWM), based on the binding specificity of a reference set of 133 PDZ domains. By using the PWM, a rank list of potential binding partners is produced from Swiss-prot protein database.

Enter the PDZ domain sequence into the text area and choose a species. Then press `Submit'.

Note: The program takes single PDZ domain currently. If your sequence contains multiple PDZ domains, please divide it such that each sequence fragment have one PDZ domain.

 Enter sequence only in FASTA format (example):
A rank list of predicted ligands are made from

Structural Bioinformatics Lab.