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This web service predicts the binding specificity of a query PDZ domain. The program automatically extracts the pocket residues of a PDZ domain from a query sequence and generates a position weight matrix (PWM), based on the binding specificity of a reference set of 133 PDZ domains. By using the PWM, a rank list of potential binding partners is produced from Swiss-prot protein database.Enter the PDZ domain sequence into the text area and choose a species. Then press `Submit'.
Structural Bioinformatics Lab.