|
|
| Speaker |
Title |
Date |
|
|
Donghyo Kim
|
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
| Journal |
Nature Communications 2019 |
|
| Author |
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark & Haiyuan Yu |
|
2019-11-11 |
|
Heetak Lee
|
Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism
| Journal |
Nature Communications 2019 |
|
| Author |
Karin Ortmayr, Sebastien Dubuis, and Mattia Zampieri |
|
2019-11-05 |
|
Min Hyuk Park
|
Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes.
| Journal |
BioRxiv(2019): 531210. |
|
| Author |
Karczewski, K. J., Francioli, L. C., Tiao, G., Cummings, B. B., Alfldi, J., Wang, Q., ... & Gauthier, L. D. |
|
2019-10-22 |
|
Doyeon Ha
|
Discovering genetic interactions bridging pathways in genome-wide association studies
| Journal |
Nature Communications (2019) |
|
| Author |
Gang Fang, Wen Wang, Vanja Paunic, ..., Vipin Kumar and Chad L. Myers |
|
2019-10-16 |
|
Kwanghwan Lee
|
Cell Systems(2019)
| Journal |
[attachment:KH_journal_club_20191008.pptx PPT] |
|
| Author |
Taroni, Jaclyn N Grayson, Peter C Hu, Qiwen Eddy, ..., MultiPLIER: A Transfer Learning Framework for Transcriptomics Reveals Systemic Features of Rare Disease |
|
2019-10-08 |
|
Seong Kyu Han
|
Pan-cancer deconvolution of tumour composition using DNA methylation
| Journal |
Nat Commun. 2018 Aug 13;9(1):3220 |
|
| Author |
Chakravarthy A, Furness A, ... , Fenten TR |
|
2019-10-01 |
|
Donghyo Kim
|
Harmonious genetic combinations rewire regulatory networks and flip gene essentiality
| Journal |
Nature communications 2019 |
|
| Author |
Aaron M. New & Ben Lehner |
|
2019-09-24 |
|
Heetak Lee
|
Estimating dispensable content in the human interactome
| Journal |
Nature Communications 2019 |
|
| Author |
Mohamed Ghadie and Yu xia |
|
2019-09-17 |
|
Jungho Kong
|
Changes in gene expression predictably shift and switch genetic interactions
| Journal |
Nature Communications 2019 |
|
| Author |
Xianghua Li, Jasna Lalic, Pablo Baeza-Centurion, Riddhiman Dhar & Ben Lehner |
|
2019-09-11 |
|
Minhyuk Park
|
Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects
| Journal |
Nature Communications 2019 |
|
| Author |
Phuong A. Nguyen, David A. Born, Aimee M. Deaton, Paul Nioi & Lucas D. Ward |
|
2019-09-04 |
|
Doyeon Ha
|
Detecting repeated cancer evolution from multi-region tumor sequencing data
| Journal |
Nature Methods 2018 |
|
| Author |
Giulio Caravagna, Ylenia Giarratano... Guido Sanguinetti and Andrea Sottoriva |
|
2019-08-28 |
|
Kwanghwan Lee
|
Improving the diagnostic yield of exome- sequencing by predicting genephenotype associations using large-scale gene expression analysis
| Journal |
Nature Communications 2019 |
|
| Author |
Patrick Deelen, Sipko van Dam, Johanna C. Herkert, et al. |
|
2019-08-13 |
|
Jungho Kong
|
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development
| Journal |
Nature Communications 2016 |
|
| Author |
Ivan V. Ozerov, Ksenia V. Lezhnina, Evgeny Izumchenko, Artem V. Artemov, Sergey Medintsev, Quentin Vanhaelen, Alexander Aliper, Jan Vijg, Andreyan N. Osipov, Ivan Labat, Michael D. West, Anton Buzdin, Charles R. Cantor, Yuri Nikolsky, Nikolay Borisov, Irina Irincheeva, Edward Khokhlovich, David Sidransky, Miguel Luiz Camargo, Alex Zhavoronkov |
|
2019-08-06 |
|
Donghyo Kim
|
Protein interaction networks revealed by proteome coevolution
| Journal |
Science 2019 |
|
| Author |
Qian Cong, Ivan Anishchenko, Sergey Ovchinnikov, David Baker |
|
2019-07-30 |
|
Heetak Lee
|
!PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data
| Journal |
Genome medicine 2019 |
|
| Author |
Elena Pieiro-Yez, ..., Alfonso Valencia, Manuel Hidalgo, Daniel Glez-Pea, and Ftima Al-Shahrour |
|
2019-07-24 |
|
|
