Evolutionary Systems Biology

Date: 2020.02.12 - 2020.02.14
Location:
Wellcome Trust Genome Campus, UK

Title: Regulatory network rewiring explains the phenotypic evolution between human and model organism
Presenter
: Doyeon Ha
Authors
: Doyeon Ha, Seong Kyu Han, Donghyo Kim and Sanguk Kim

Title: Identification of cancer type-specific driver mutations using sequence co-evolution analysis
Presenter
: Donghyo Kim
Authors
: Donghyo Kim, Doyeon Ha, Seong Kyu Han and Sanguk Kim

Title: Visible machine learning approach to predict anticancer drug efficacy in cancer patients using organoid models
Presenter
: Jungho Kong
Authors
: Jungho Kong, Heetak Lee, Donghyo Kim, Seong Kyu Han, Kunyoo Shin and Sanguk Kim

 

Asian Bioinformatics Consortium (ABC) Symposium

Date: 2019.08.21 - 2019.08.24
Location:
Guizhou Normal University (Hua Xi Campus), China

Title: Evolution of functional modules and regulatory networks: Understanding genotype-phenotype relationship
Presenter
: Sanguk Kim
Authors
: Seong Kyu Han, Doyeon Ha and Sanguk Kim

 

The 16th Korea-Japan_China Bioinformatics Symposium 2018

Date: 2018.08.29 - 2018.08.31
Location:
Sokendai, Hayama, Japan

Title: A systematic gene-phenotype comparison between human and mouse to find accurate phenologs  
Presenter
: Sanguk Kim
Authors
: Seong Kyu Han, Doyeon Ha and Sanguk Kim

 

ISMB 2018; 26th Conference on Intelligent Systems for Molecular Biology

Date: 2018.07.06 - 2018.07.10
Location: Chicago, United States

Title: Identification of cancer essential genes through integration of cell-line specific network
Presenter
: Kwanghwan Lee
Authors
: Kwanghwan Lee and Sanguk Kim

Title: Identification of druggable PPIs using domain-mediated interaction interfaces
Presenter
: Heetak Lee
Authors
: Heetak Lee and Sanguk Kim

Title: Predicting mutational impact of disease-associated variants based on the network of evolutionary coupled residues
Presenter
: Donghyo Kim
Authors
: Donghyo Kim and Sanguk Kim

Title: Transcriptomic changes in network partners of orthologous genes represent phenotypic differences between species
Presenter
: Doyeon Ha
Authors
: Doyeon Ha and Sanguk Kim

 

10th Annual RECOMB/ISCB Confernce on Regulatory & Systems Genomics

Date: 2017.11.19 - 2017.11.21
Location: New York, USA

Title: Biological functions rather than individual genes can explain the phenotypic differences observed between human and mouse orthologous genes
Presenter
: Seong Kyu Han
Authors
: Seong Kyu Han and Sanguk Kim

Title: Identification of biomarkers and prediction of survival based on exome sequencing of the mouse model of aggressive bladder cancer
Presenter
: Jung Ho Kong
Authors
: Jung Ho Kong, Donghyo Kim, Kunyoo Shin and Sanguk Kim

 

The 15th Korea-Japan-China Bioinformatics Symposium 2017

Date: 2017.06.21 - 2017.06.22
Location: Koreana Hotel, Seoul, South Korea

Title: Evolution of the genotype-phenotype relationship of human disease genes
Presenter
: Sanguk Kim
Authors
: Seong Kyu Han and Sanguk Kim

 

Genome Evolution at Mishima

Date: 2017.03.27 - 2017.03.29
Location: National Institute of Genetics, Mishima, Japan

Title: Network evolution analysis to understand phenotype divergence between human and model organisms
Presenter
: Sanguk Kim
Authors
: Seong Kyu Han and Sanguk Kim

International Conference on Systems Biology 2016

Date: 2016.9.15 - 2015.9.21
Location: Barcelona, Spain

Title: Types of domain mediated interaction explain genotype-phenotype relationships
Presenter
: Heetak Lee
Authors
: Heetak Lee and Sanguk Kim

Title: Network evolution and phenotype changes between species
Presenter
: Seong Kyu Han
Authors
: Seong Kyu Han, Donghyo Kim, and Sanguk Kim

Title: Predicting the functional impact of protein mutations using coevolutionary signals
Presenter
: Donghyo Kim
Authors
: Donghyo Kim and Sanguk Kim

 

International School and Conference on Network Science 2016

Date: 2016.5.30 - 2016.6.3
Location: Seoul, Korea

Title: Popularity and similarity in network evolution explain the architecture of core/attachment in protein complexes
Presenter
: Inhae Kim
Authors
: Inhae Kim and Sanguk Kim

Title: Network evolution and understanding human gene-phenotype relationship
Presenter
: Seong Kyu Han
Authors
: Seong Kyu Han, Donghyo Kim, and Sanguk Kim

Title: Phenotypic role of domain mediated interactions through community detection on the structural interaction network
Presenter
: Heetak Lee
Authors
: Heetak Lee and Sanguk Kim

The 29th Annual Symposium of Protein Society

Date: 2015.7.22 - 2015.7.25
Location: Barcelona, Spain

Title: Comprehesive protein domain analysis to map cancer-type-specific somatic mutations
Presenter
: Jihye Hwang
Authors
: Jihye Hwang, Sangjin Han, Inhae Kim, Sanguk Kim

Title: Identification of transient protein complexes by using intrinsic disorder and network topology
Presenter
: Inhae Kim
Authors
: Inhae Kim, Sangjin Han, Jihye Hwang, Sanguk Kim

Title: Identification of cancer-type-specific modules comprised of cancer-type-specific variants through phenotype similarity between cancer types
Presenter
: Sangjin Han
Authors
: Sangjin Han, Jihye Hwang, Inhae Kim, Sanguk Kim

 

The 15th Annual International Proteomics Conference

Date: 2015.3.26 - 2015.3.27
Location: Seoul, Korea

Title: Protein comiplexes differ in the density and the modularity of protein-protein interactions to achieve various functions
Presenter
: Inhae Kim
Authors
: Inhae Kim, Sanguk Kim

The 13th Human Proteome Organization World Congress

Date: 2014.10.05 - 2014.10.08
Location: Madrid, Spain

Title: Weak linear motif-mediated interactions contribute to the rearrangement of modular architecture in complex protein interaction networks
Presenter
: Inhae Kim
Authors
: Inhae Kim, Heetak Lee, Seong Kyu Han, Sanguk Kim

Title: Gene essentiality on model organism explains clinical severity of human genetic disorders
Presenter
: Seong Kyu Han
Authors
: Seong kyu Han, Inhae Kim, Sanguk Kim

 

The 28th Annual Symposium of the Protein Society

Date: 2014.07.27 - 2014.07.30
Location: San Diego, CA, the U.S.

Title: Domain exchange between membrane and soluble proteins contributes to expand intercellular communication network
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Inhae Kim, James U. Bowie, Sanguk kim

 

The 58th Annual Meeting of Biophysical Society

Date: 2014.02.15 - 2014.02.19
Location: San Francisco, CA, USA

Title: Analysis of protein domains and gene essentiality
Presenter
: Hee-tak Lee
Authors
: Hee-tak Lee, Seong-kyu Han, Inhae Kim, Hyun-Jun Nam, Sanguk Kim

The 5th International Symposium on IT Convergence Engineering (ISITCE 2013)

Date: 2013.07.11 - 2013.07.12
Location: Pohang, Korea

Title: Domain exchange between membrane and soluble proteins contributes to metazoan evolution
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Hee-Tak Lee, Jinho Kim, James U. Bowie, Sanguk Kim

Title: Improving module identification in protein-protein interaction networks by using interaction strengths
Presenter
: Inhae Kim
Authors
: Inhae Kim, Hyun-Jun Nam, Jihye Hwang, and Sanguk Kim

Title: Modular architecture of gene essentiality reveals clinical severity of human genetic diseases
Presenter
: Seong Kyu Han
Authors
: Seong Kyu Han, and Sanguk Kim

 

Annual Conference of Society for Molecular Biology and Evolution (SMBE 2013)

Date: 2013.07.07 - 2013.07.11
Location: Chicago, IL, USA

Title: Network evolution and gene essentiality changes
Presenter
: Sanguk Kim
Authors
: Sanguk Kim

 

A Meeting on Membrane Protein Folding (2013)

Date: 2013.05.19 - 2012.05.22
Location: Seoul, Korea

Title: Fold Space and Function Annotation of Membrane Proteins
Speaker
: Sanguk Kim
Authors
: Hyun-Jun Nam, Seong Kyu Han, James Bowie, and Sanguk Kim

The 13th International Conference on Systems Biology (ICSB 2012)

Date: 2012.08.19 - 2012.08.23
Location: Toronto, Canada

Title: Network rewiring has a significant impact on gene essentiality changes
Presenter
: Jinho Kim
Authors
: Jinho Kim, Inhae Kim, Seong Kyu Han, Young-Eun Shin, Jihye Hwang, and Sanguk Kim

Title: Evolutionary analysis of domain-linear motif interactions revealed the modular architecture of protein-protein interaction networks
Presenter
: Inhae Kim
Authors
: Inhae Kim, Jinho Kim, Jihye Hwang, Hyun-Jun Nam, and Sanguk Kim

 

4th International Symposium on IT Convergence Engineering (ISITCE 2012)

Date: 2012.07.12 - 2012.07.13
Location: Seoul, Korea

Title: Network medicine to predict drug side effects:Functional diversity of membrane proteins is mediated by dynamic rewiring of protein interactions
Presenter
: Jihye Hwang
Authors
: Jihye Hwang, Murat Artan, Sanguk Kim

Title: Analysis of shared structure and function between membrane and water-soluble proteins for drug design
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Jinho Kim, Jihye Hwang, James U. Bowie, Sanguk Kim

Title: Analysis of interaction strengths and global architecture in protein-protein interaction networks
Presenter
: Inhae Kim
Authors
: Inhae Kim, Jinho Kim, Jihye Hwang, Hyun-Jun Nam, and Sanguk Kim

Title: Multipath in protein interaction network improved the understanding of the comorbidity of genetic diseases
Presenter
: Young-Eun Shin
Authors
: Young-Eun Shin, Jinho Kim, Inhae Kim, and Sanguk Kim

22nd International Conference on Genome Informatics (GIW 2011)

Date: 2011.12.05 - 2011.12.07
Location: Pusan, Korea

Title: Global Sequence Homology Detection Using Word Conservation Probability
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Dae-Kyum Kim, Sanguk Kim

Title: Comparative network analysis reveals the mechanism of gene essentiality changes
Presenter
: Jinho Kim
Authors
: Jinho Kim, Seong Kyu Han, Young-Eun Shin, Solip Park, Jihye Hwang, Jaeseong Yang, Sanguk Kim

Title: Evolutionary connections of disease modules implicate in the comorbidity
Presenter
: Solip Park
Authors
: Solip Park, Jae-Seong Yang, Jihye Hwang, Young-Eun Shin, Sung Key Jang, Sanguk Kim

19th Annual Interanational Conference on Intelligent Systems for Molecular Biology and 10th European Conference on Computational Biology (ISMB/ECCB 2011)

Date: 2011.07.17 - 2011.07.19
Location: Vienna, Austria

Title: Evolution of domain-linear motif interactions shapes the modular architecture of protein-protein interaction networks
Presenter
: Inhae Kim
Authors
: Inhae Kim, Seong Kyu Han, Jinho Kim, Jihye Hwang, Hyun-Jun Nam, Sanguk Kim

Title: Connection patterns in protein-protein interaction network reveal the phenotypic relationships among human diseases
Presenter
: Young-Eun Shin
Authors
: Young-Eun Shin, Solip Park, Jae-Seong Yang, Jinho Kim, Sanguk Kim

3rd International Symposium on IT Convergence Engineering (ISITCE 2011)

Date: 2011.07.14 - 2011.07.15
Location: Pohang, Korea

Title: E-health for disease prognosis: Connection patterns in protein-protein interaction network reveal phenotype similarity and comorbidity of genetic diseases
Presenter
: Young-Eun Shin
Authors
: Young-Eun Shin, Solip Park, Jae-Seong Yang, Jinho Kim, Sanguk Kim

Title: E-health and network medicine: Network position can identify mitochondrial disease genes
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Jinho Kim, Jouhyun Jeon, Solip Park, Jihye Hwang, Youngeun Shin, Sanguk Kim

Title: Protein Localization as a principal feature of comorbidity
Presenter
: Solip Park
Authors
: Solip Park, Jae-Seong Yang, Young-Eun Shin, Inhae Kim, Jihye Hwang, Sung Key Jang, Sanguk Kim

Title: Comparative genomics between yeast and mouse reveals the etiology of genetic diseases
Presenter
: Jinho Kim
Authors
: Jinho Kim, Seong Kyu Han, Young-Eun Shin, Solip Park, Jihye Hwang, Jae-Seong Yang, Sanguk Kim

Title: Network medicine to predict drug side effects: Rewiring of protein-protein interaction network of plasma membrane proteins explains drug side effects
Presenter
: Jihye Hwang
Authors
: Jihye Hwang, Jinho Kim, Jouhyun Jeon, Sanguk Kim

Title: Structural property of protein-protein interactions explains functional associations at the molecular and phenotypic levels
Presenter
: Inhae Kim
Authors
: Inhae Kim, Seong Kyu Han, Jinho Kim, Jihye Hwang, Hyun-Jun Nam, Sanguk Kim

Title: E-health and drug target discovery: Analysis of fold space of membrane proteins to find the template structures for drug target discovery
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Jouhyun Jeon, Jae-Seong Yang, Sanguk Kim

IX European Symposium of The Protein Society

Date: 2011.05.22 - 2011.05.26
Location: Stockholm, Sweden

Title: Membrane proteins share fold space with soluble proteins to expand their functional diversity during evolution
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Jouhyun Jeon, Jae-Seong Yang, Sanguk Kim

The 24th Annual Symposium of the Protein Society

Date: 2010.08.01 - 2010.08.05
Location: San Diego, California, U.S.A

Title: Tissue Specific Interactions of Plasma Membrane Proteins as the Mechanism of Functional Diversity
Presenter
: Jihye Hwang
Authors
: Jihye Hwang, Young-Eun Shin, Jinho Kim, Solip Park, Sanguk Kim

Title: Protein conformational changes are derived from the network of evolutionarily coupled residues
Presenter
: Jouhyun Jeon
Authors
: Jouhyun Jeon, Young-Eun Shin, Jihye Hwang, Yoon Sup Choi, Jae-Seong Yang, Hyun-Jun Nam, and Sanguk Kim

Title: Systematic analysis of human PDZ domain-ligand interaction network and their localization
Presenter
: Jinho Kim
Authors
: Jinho Kim, Jae-seong Yang, Solip Park, Yoon Sup Choi, Jouhyun Jeon, Jihye Hwang, Sanguk Kim

International conference on Intelligent Systems for Molecular Biology (ISMB)

Date: 2010.07.09 - 2010.07.13
Location: Boston, U.S.A

Title: The implications of protein subcellular localization for disease profiling
Presenter
: Solip Park
Authors
: Solip Park, Jae-seong Yang, Jihye Hwang, Young-Eun Shin, Yeonjoo Yoo, Sung Key Jang, Sanguk Kim

Title: Systematic analysis of mitochondrial proteins involved in the communication to the cell
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Jouhyun Jeon, Solip Park, Yun-joo Yoo, Jinho Kim, Youngeun Shin, Sanguk Kim

2010 KSBMB Annual Meeting

Date: 2010.05.17 - 2010.05.19
Location: Seoul, Korea

Title: The importance of protein subcellular localization for disease profiling
Presenter
: Sanguk Kim
Authors
: Solip Park, Jae-seong Yang, Jihye Hwang, Yeonjoo Yoo, Young-Eun Shin, Sung Key Jang and Sanguk Kim

Title: The important role of protein subcellular localization in disease profiling
Presenter
: Solip Park
Authors
: Solip Park, Jae-seong Yang, Jihye Hwang, Yeonjoo Yoo, Young-Eun Shin, Sung Key Jang and Sanguk Kim

Title: Understanding the mitochondrial proteins involved in the communication to the cell through network biology
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Jouhyun Jeon, Solip Park, Yun-joo Yoo, Jinho Kim, Yonghwan Choi, Youngeun Shin, Sanguk Kim

Title: Comprehensive analysis of human PDZ domain-ligand interaction network
Presenter
: Jinho Kim
Authors
: Jinho Kim, Jae-Seong Yang, Solip Park, Yoon Sup Choi, Jouhyun Jeon, Jihye Hwang, Sanguk Kim

Title: New insight into the fold space of membrane proteins revealed by structural comparison with soluble proteins
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Jouhyun Jeon, Jae-Seong Yang and Sanguk Kim

Title: Tissue specific expression of plasma membrane proteins and their functional diversity
Presenter
: Jihye Hwang
Authors
: Jihye Hwang, Jinho Kim, Solip Park, Sanguk Kim

Title: Insights into protein flexibility: The relationship between evolutionarily coupled residues and conformational changes
Presenter
: Jouhyun Jeon
Authors
: Jouhyun Jeon, Inhae Kim, Yoon Sup Choi, and Sanguk Kim

Biophysical Society 54th Annual Meeting

Date: 2010.02.20 - 2010.02.24
Location: U.S.A

Title: Evolutionary analysis of conformational changes in allosteric proteins
Presenter
: Jouhyun Jeon
Authors
: Jouhyun Jeon, Yoon Sup Choi, Jae-Seong Yang, Hyun-Jun Nam, and Sanguk Kim

7th Pusan Workshop on Proteome Biophysics & 1st Asia-Pacific IUP Symposium

Date: 2009.12.05 - 2009.12.06
Location: Korea

Title: Evolution of protein dynamics: Role of residue interaction networks in protein allostery
Presenter
: Sanguk Kim
Authors
: Sanguk Kim

2009 International Symposium on IT Convergence Engineering

Date: 2009.10.16 - 2009.10.17
Location: Korea

Title: Quantitative interaction prediction revealed the genome-wide selectivity preferences of human PDZ domains
Presenter
: Jinho Kim
Authors
: Jinho Kim, Jaeseong Yang, Jouhyun Jeon, Sanguk Kim

Title: Identification of functional residues in Major Facilitator Superfamily (MFS) transporters using evolutionary features
Presenter
: Jouhyun Jeon
Authors
: Jouhyun Jeon, Jae-seong Yang, and Sanguk Kim

Title: Identification of eukaryote-specific mitochondrial proteome through data integration and phylogenetic profiling
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Jouhyun Jeon, Jinho Kim, Yonghwan Choi, and Sanguk Kim

Title: Functional and evolutionary relationship between membrane and soluble proteins
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Yoon Sup Choi, Jouhyun Jeon, Jinho Kim, Jae-Seong Yang, and Sanguk Kim

The 9th POSTECH-KYUTECH Joint Workshop on Neuroinformatics

Date: 2009.08.25
Location: Korea

Title: Bioinformatic studies of protein sequence, structure, and function
Presenter
: Sanguk Kim
Authors
: Sanguk Kim

2009 The Protein Society Symposium

Date: 2009.07.24 - 2009.07.29
Location: U.S.A

Title: Intrinsically unstructured C-terminal regions of transmembrane PDZ ligands play an important role in clustering scaffold proteins
Presenter
: Jinho Kim
Authors
: Jinho Kim, Jihye Hwang, Yoon Sup Choi, Hyun-Jun Nam, Sanguk Kim

Title: Analysis of eukaryote-specific mitochondrial protein networks through data integration and phylogenetic profiling
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Doo-young Ahn, Jouhyun Jeon, Solip Park, Sanguk Kim

2009 European Symposium of the Protein Society

Date: 2009.06.14 - 2009.06.18
Location: Switzerland

Title: Genome-wide selectivity preferences of human PDZ domain-ligand interaction
Presenter
: Sanguk Kim
Authors
: Jinho Kim, Jae-Seong Yang, Jouhyun Jeon, Sanguk Kim

The 66th KSBMB Annual Meeting

Date: 2009.05.12 - 2009.05.13
Location: Korea

Title: Identification of eukaryote-specific mitochondrial proteome through data integration and phylogenetic profiling
Presenter
: Jae-Seong Yang
Authors
: Jae-Seong Yang, Jouhyun Jeon, Jinho Kim, Yonghwan Choi, and Sanguk Kim

Title: Functional and evolutionary relationship between membrane and soluble proteins
Presenter
: Hyun-Jun Nam
Authors
: Hyun-Jun Nam, Yoon Sup Choi, Jouhyun Jeon, Jinho Kim, Jae-Seong Yang, and Sanguk Kim

Title: Assessing systems properties of human mitochondria through a quantitative proteomics analysis
Presenter
: Jouhyun Jeon
Authors
: Jouhyun Jeon, Jae-Seong Yang, Yun-Joo Yoo, Youngmi Kim Pak, and Sanguk Kim

Title: A new systematic approach to identify functions of human extracellular proteins using yeast
Presenter
: Sol-Ip Park
Authors
: Sol-Ip Park, OK-Kyu Song, Hyung-Jin Lee, Vit Kim, Jae-Seong Yang, Doo-Young Ahn, Sanguk Kim, Sung-Key Jang

Title: Rational design of binding determinant specific non-antibody protein scaffolds: EGFR inhibitors with novel mechanism of action
Presenter
: Yoon Sup Choi
Authors
: Yoon Sup Choi, Sumin Yoon, Jinho Kim, So Jeong Yun, Pann-Chill Suh, Sanguk Kim, Junho Chung and Sung Ho Ryu

Title: Intrinsically unstructured C-terminal regions of transmembrane PDZ ligands play an important role in clustering
Presenter
: Jinho Kim
Authors
: Jinho Kim, Yoon Sup Choi, Hyun-Jun Nam, Jihye Hwang, Sanguk Kim

First Korea-Japan Seminars on Biomolecular Sciences

Date: 2009.03.01
Location: Korea

Title: Systematic design of novel protein binding interfaces
Presenter
: Sanguk Kim
Authors
: Sanguk Kim

2009 IUPS International Conference of Physiological Science

Date: 2009.01.16
Location: Korea

Title: Bioinformatics approaches for membrane protein channel and transporter
Presenter
: Sanguk Kim
Authors
: Sanguk Kim

Asia Pacific Bioinformatics Conference

Date: 2009.01.11 - 2009.01.14
Location: China

Title: Evolutionary conservation in multiple faces of protein interaction
Presenter
: Sanguk Kim
Authors
: Sanguk Kim, Yoon Sup Choi, Jae-Seong Yang, Sung Ho Kim